This paper reviewed genetic, neurodevelopmental, and neurobiological perspectives\nto understand the etiology and relevant treatment approaches of schizophrenia. Although\ngenetic and neurodevelopmental theories provide a substantial contribution\nto the etiology of schizophrenia, neurobiological one has its dominant stance in\nwhich it can explain causative mechanisms of schizophrenia, identify targets for\ntreatment, and predict outcomes well. According to the neurobiology, onset and\ncourse of schizophrenia are well supported by the alterations in neurotransmitters\nsuch as dopamine or serotonin. Based on this mechanism, antipsychotics have been\nwidely used as one of the treatment approaches for schizophrenia. By following up\nthe degree of patients� responses to antipsychotics, treatment outcomes could be\nevaluated or predicted. Although neurobiology seldom provides information about\nidentification or prevention of risk factors about schizophrenia compared to genetic\nand neurodevelopmental approaches, it has well-established scientific foundations,\nability to guide treatment, applicability across age and culture, and usefulness as a\nresearch framework.
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